Portfolio item number 1
Published:
Short description of portfolio item number 1
Posts by Collection
portfolio
Portfolio item number 2
Published:
Short description of portfolio item number 2
publications
Paper Title Number 1
Published in Journal 1, 2009
This paper is about the number 1. The number 2 is left for future work.
Recommended citation: Your Name, You. (2009). "Paper Title Number 1." Journal 1. 1(1). http://academicpages.github.io/files/paper1.pdf
Paper Title Number 2
Published in Journal 1, 2010
This paper is about the number 2. The number 3 is left for future work.
Recommended citation: Your Name, You. (2010). "Paper Title Number 2." Journal 1. 1(2). http://academicpages.github.io/files/paper2.pdf
Paper Title Number 3
Published in Journal 1, 2015
This paper is about the number 3. The number 4 is left for future work.
Recommended citation: Your Name, You. (2015). "Paper Title Number 3." Journal 1. 1(3). http://academicpages.github.io/files/paper3.pdf
Deciphering the roles of Fat and Dachsous planar polarity and cell shape in arranging the apical microtubule network
Published in Molecular Biology of the Cell, 2023
In epithelial cells, planar polarisation of subapical microtubule networks is thought to be important for both breaking cellular symmetry and maintaining the resulting cellular polarity. Studies in the Drosophila pupal wing and other tissues have suggested two alternative mechanisms for specifying network polarity. On one hand mechanical strain and/or cell shape have been implicated as key determinants, on the other the Fat-Dachsous planar polarity pathway has been suggested to be the primary polarising cue. Using quantitative image analysis in the pupal wing, we reassess these models. We found that cell shape was a strong predictor of microtubule organisation in the developing wing epithelium. Conversely Fat-Dachsous polarity cues do not play any direct role in the organisation of the subapical microtubule network, despite being able to weakly recruit the microtubule minus-end capping protein Patronin to cell boundaries. We conclude that any effect of Fat-Dachsous on microtubule polarity is likely to be indirect, via their known ability to regulate cell shape.
Recommended citation: Ramirez Moreno, M; Hunton, R; Strutt, D and Bulgakova, NA (2023). " "Deciphering the roles of cell shape and Fat and Dachsous planar polarity in arranging the Drosophila apical microtubule network through quantitative image analysis"." Molecular Biology of the Cell. 1(1). [http://academicpages.github.io/files/paper1.pdf](https://www.molbiolcell.org/doi/10.1091/mbc.E22-09-0442?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed)
Tau-mediated axonal degeneration is prevented by activation of the WldS pathway Permalink
Published in Brain Communications, 2023
Download here
talks
teaching
Teaching experience 1
Undergraduate course, University 1, Department, 2014
This is a description of a teaching experience. You can use markdown like any other post.
Teaching experience 2
Workshop, University 1, Department, 2015
This is a description of a teaching experience. You can use markdown like any other post.